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<p class="MsoNormal">Hi all,<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">I was made aware of this research talk from Prof Juewen Liu from Waterloo taking place next week in Chemistry that could be of interest for many of us in Physics.<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">Best wishes,<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">Stefan<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal"><span style="mso-fareast-language:EN-GB"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="mso-fareast-language:EN-GB">===========================<o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-fareast-language:EN-GB">Professor Stefan Kuhr<o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-fareast-language:EN-GB">Head of Department<o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-fareast-language:EN-GB">University of Strathclyde<o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-fareast-language:EN-GB">Department of Physics<o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-fareast-language:EN-GB">Glasgow <o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-fareast-language:EN-GB">G4 0NG<o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-fareast-language:EN-GB">United Kingdom<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="DE" style="mso-fareast-language:EN-GB"><a href="mailto:Stefan.kuhr@strath.ac.uk"><span lang="EN-GB">Stefan.kuhr@strath.ac.uk</span></a></span><span style="mso-fareast-language:EN-GB"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-fareast-language:EN-GB">Phone: +44 141 548 3364<o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-fareast-language:EN-GB"><o:p> </o:p></span></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">Prof Juewen Liu from Waterloo will be visiting on the 24<sup>th</sup> of March and giving a talk in TG 227 at 2 pm. Juewen is a world leader in the field of aptamers and nanoparticles with an amazing publication record in the field. If
anyone would like to meet with him please do let Duncan Graham know.<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">Talk details and more info on Juewen:<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal" style="margin-bottom:8.0pt;text-align:justify;line-height:11.75pt">
<b><span style="color:#212121;mso-fareast-language:EN-GB">Biosensors based on aptamers and gold nanoparticles</span></b><span style="color:#212121;mso-fareast-language:EN-GB"><o:p></o:p></span></p>
<p class="MsoNormal" style="margin-bottom:8.0pt;text-align:justify;line-height:11.75pt">
<span style="color:#212121;mso-fareast-language:EN-GB">Interfacing DNA with gold nanoparticles (AuNPs) has produced a diverse range of biosensors, imaging agents, drug delivery systems, and new materials. AuNPs are particularly attractive because of their low
toxicity and unique optical, electric and catalytic properties. Using fluorescently labeled oligonucleotides as probes, we measured the kinetics of DNA adsorption, desorption as well as adsorption isotherm as a function of salt, pH, and temperature. An important
application of such fundamental studies is the attachment of DNA to AuNPs. Highly efficient DNA adsorption can be achieved at low pH and freezing. In addition, we studied aptamer-based sensors using AuNPs for signal production and revealed some potential artifacts.
In the second part of the talk, our recent work on selection of DNA aptamers for binding to small molecular targets will be presented.<o:p></o:p></span></p>
<p class="MsoNormal" style="margin-bottom:8.0pt;text-align:justify;mso-line-height-alt:11.75pt">
<b><span style="font-size:12.0pt;color:#212121;mso-fareast-language:EN-GB">Biography:</span></b><span style="color:#212121;mso-fareast-language:EN-GB"><o:p></o:p></span></p>
<p class="MsoNormal" style="margin-bottom:8.0pt;text-align:justify;line-height:11.75pt">
<b><span style="color:#212121;mso-fareast-language:EN-GB">Juewen Liu </span></b><span style="color:#212121;mso-fareast-language:EN-GB">received his Ph.D. degree from the University of Illinois at Urbana-Champaign in 2005. After postdoctoral research at Sandia
National Labs and the University of New Mexico, he joined the Department of Chemistry at the University of Waterloo in 2009. Dr. Liu is currently a full professor at the University of Waterloo. He is interested in aptamers and biosensors. He received a Fred
Beamish Award (2014) and a McBryde Medal (2018) from the Canadian Society for Chemistry for his contribution in bioanalytical chemistry. He is a College member of the Royal Society of Canada. He serves as a Section Editor for <i>Biosensors & Bioelectronics</i>,
and a Contributing Editor for <i>TrAC Trends in Analytical Chemistry</i>. He has published over 400 papers, receiving over 38,000 citations with an H-index of 92, and is a Clarivate Highly Cited Researcher in 2022. <o:p></o:p></span></p>
<p class="MsoNormal"><o:p> </o:p></p>
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